Wednesday 10 January 2018

Natural Superdisintegrants on the Rise with Extensive R&D

Superdisintegrants allow speedy drug release by disintegrating tablets or capsules into smaller particles and creating a greater surface area. They are used as viscosity enhancing agents in drug loaded films. Moreover, their addition to drugs results in high nanoparticle surface area retention and drug content uniformity. Owing to these factors, superdisintegrants are emerging as superior alternatives to conventional viscosity enhancing agents, which is likely to keep their demand high through 2025.

Superdisintegrants Market

 Consumption of Mouth-dissolving Films Mounting

On the basis of products, superdisintegrants can be divided into croscarmellose sodium, sodium starch glycolate, crospovidone, ion exchange resin, and others, including natural superdisintegrants. Demand for crospovidone is likely to remain strong through 2025. The ability of this product to stabilize the amorphous state of drugs is contributing to its sales. Furthermore, crospovidone exhibits superior disintegration and dissolution enhancing effect.

However, natural superdisintegrants such as gellan gum, isapghula husk, and locust bean gum are anticipated to witness continual upsurge in demand in coming years. Their high hydrophilic nature leads to rapid disintegration of tablets. They also offer minimum side effects. Researchers and superdisintegrant manufacturers are focusing on constant research activities to develop novel and modified natural disintegrating agents.

The common dosage forms of superdisintegrants are tablets, capsules, and mouth-dissolving films. Consumption of mouth-dissolving films is expected to rise drastically through 2025. Their advantages such as accurate dosing, improved patient compliance, rapid onset of action, and availability of larger surface area for rapid disintegration and dissolution in the oral cavity are supporting their demand.

Market Insights

As per the findings of Grand View Research, Inc.; the global superdisintegrants market is anticipated to reach a valuation of USD 487 million by 2025. Market participants are allocating heft funds to R&D activities to develop novel superdisintegrants. These formulae are then incorporated by pharmaceutical companies into their offerings, which can work in favor of the market. For instance, among the Omyapharm multifunctional excipient platform showcased by Omya at the Convention on Pharmaceutical Ingredients (CPhI) 2017 in Frankfurt, its offering, 500-DG OG, contains a superdisintegrant which ensures fast disintegration and good compactibility. Orally dispersible tablets manufactured from this excipient disintegrate in less than 10 seconds.

Government policies and rising prevalence of chronic disorders are promoting the consumption of pharmaceuticals, which can provide a tremendous push to the market. North America is expected to account for a substantial share in the global arena throughout the forecast horizon, thanks to domicile of a large number of key players.

Some of the prominent players in the market are FMC Corporation, Nippon Soda Co., Ltd., BASF SE, The Dow Chemical Company, and Huber Corporation.

In-Depth Research Report On Superdisintegrants Market:
https://www.grandviewresearch.com/industry-analysis/superdisintegrants-market

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