10 September 2018: Protein purification is a set of methods used for isolating or extracting proteins from complex mixtures such as animal or plant tissues, cells, or whole organism. The process of purification helps separate protein and non-protein parts of the mixture. Purification and extraction are vital components of any protein-specific research. However, the methods usually depend on the nature of both the solution and protein. Chromatography, ultrafiltration, western blotting, precipitation, and electrophoresis are the key methods or technologies.
Chromatography: A Widely used Method
Chromatography was the dominant protein purification and isolation technology in the past. It is considered as one of the most accurate and sensitive methods. The technology is expected to witness significant growth in the years to come. Many companies are focusing on commercialization of their new products based on chromatography to increase their business across different application sectors and regions.
For example, a new affinity chromatography-based method has been developed at the University of Alabama. This method helps enhance high-activity, high-purity, and high-yield purification of complex proteins. According to a professor of biochemistry and molecular genetics at the university, this method offers a number of advantages to both researchers and the pharma industry. This one-step purification process is expected to overcome some major weaknesses of the existing commercially available methods.
Chromatography technology is sub-categorized into size exclusion, affinity chromatography, ion exchange, hydrophobic interaction, and reversed phase chromatography. These sub-categories help users decide the purification method depending on their applications. These technologies also find applications in primary processes for academic research. Hence, they are likely to witness a steady growth in terms of demand over the next few years.
Market Insights
Based on a research report by Grand View Research, Inc.; the global protein purification and isolation market was estimated at USD 4.7 billion in 2016. It is likely to expand at a CAGR of 8.1% by 2025. Rising research in pharmaceuticals and biotechnology for the development of advanced drugs is a key driving factor. In addition, rising need for purification kits to purify, screen, concentrate, and prepare samples in shorter period is also expected to fuel market growth. Sigma-Aldrich Corp.; Thermo Fisher Scientific; Bio-Rad Laboratories, Inc.; Norgen Biotek Corp.; and Promega Corp. are some of the key companies in the global market.
In-Depth Research Report On Protein Purification and Isolation Market:
https://www.grandviewresearch.com/industry-analysis/protein-purification-isolation-market
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