Biotechnology has made major progress for creating
substances over the recent past. Scientists all over the world use various cell
culture technologies on a daily basis. Cell culture is a method in which cells
are grown under artificial & controlled conditions. Also, the techniques
for the industrial production of biopharmaceuticals such as antibodies,
proteins, vaccines, etc. have shifted from the usual fermentation technologies
to the modern mammalian cell culture technologies. The global market for cell culture
protein surface coating is expected to grow at a healthy CAGR over the
estimated period (from 2014 to 2025). This growth is attributed to the growing
interests of scientists & biotechnology firms in the stem cell R&D.
Mammalian
Cell Culture:
The gene therapy or tissue engineering opens up new exciting
fields. Bioreactors from small- to large-scale have also been developed over
the last few years for the applications based on mammalian cell culture. The
mammalian cell culture technology is becoming a major field of the modern
biotechnology, particularly in the human health area. The term “mammalian cell
culture” is used for the cells of mammalians that are isolated from particular
tissues such as glands, liver, skin, and so on and further grown and recreated
in a man-made medium.
Fields
of Products & Applications:
Among the products, rabies, Foot-&-Mouth-Disease (FMD),
and rubella for veterinary usage and hepatitis B, viral vaccines against polio,
mumps, and measles for human usage are the important ones. The latest
advance—for the large-scale viral vaccines production with the cells dependent
on anchorage—was the advent of microcarriers in the late 60s. The latest
targets for cell-based vaccines include the herpes simplex virus, influenza,
and Human Immunodeficiency Virus (HIV). Recent improvements include DNA
vaccines or genetically-designed vaccines
Monoclonal antibodies are now an important tool for
diagnostic uses, as well as for treatment. The significance of these antibodies
as therapeutic agents has increased in recent times, as the immunogenic mouse
antibodies were substituted by chimeric, human or humanized antibodies. The
glycoprotein is another major group of mammalian cell products.
The areas of application are cancer diagnosis &
treatment, Organ Transplantation (OKT3), leukemia, rheumatoid arthritis,
multiple sclerosis, and asthma. The latest recombinant methods focus on novel
antibody formats, for instance, bivalent antibodies or fragmented antibodies
(FAb’s), with a wide application range.
Market
Insights:
The growing demands for biopharmaceutical products
(vaccines, antibodies, etc.) created using the help of cell culture technology
are expected to augment the cell culture protein surface
coating market growth. The key companies operating in the
worldwide market include Trevigen Inc.; Greiner Bio One International GmbH;
Merck KGaA; BioVision, Inc.; and PerkinElmer, Inc.
In-Depth
research report on culture protein surface coating market:
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