Thursday 10 August 2017

New FDD Approved Antipsychotic Drug for Schizophrenia & MDD Treatments

Antipsychotics, also known as major tranquilizers or neuroleptics, are a group of drugs utilized to manage & treat psychosis, including hallucinations, delusions, disordered thought or paranoia, majorly in bipolar disorder and schizophrenia treatment. The constant development of enhanced next-generation products to defeat the unwanted reactions & adverse effects of the existing products is boosting the demands for newer drugs. This factor is expected to augment the growth of the global market.

Antipsychotics Usage:

These drugs are rapidly being utilized in the management of non-psychotic disorders as well. Antipsychotics are generally effective in easing the signs of psychosis in the short-term. The long-term usage of antipsychotics is related to adverse effects, for example, metabolic syndrome, involuntary movement disorders, and gynecomastia. These drugs are also associated with the growing mortality in geriatric population base with dementia.

Rexulti (brexpiprazole) by Otsuka:

A new antipsychotic drug—Rexulti (brexpiprazole) tablets—has been approved by the U. S. Food and Drug Administration (FDA) for the treatment of people suffering from schizophrenia and also an adjunctive treatment for people suffering from Major Depressive Disorder (MDD). Brexpiprazole is a once-daily, 2nd generation or atypical oral antipsychotic that was developed by Otsuka and co-developed by Otsuka and Lundbeck.

It is presumed to work through a blend of antagonist activity at serotonin 5-HT2A receptors and partial agonist activity at dopamine D2 & serotonin 5-HT1A receptors. It also displays high affinity for these two receptors, as well as for noradrenaline alpha1B/2C receptors.

Future Market Insights:

The factors such as the introduction of novel antipsychotic drugs and high investments in the R&D for the development of even better drugs are expected to augment the growth of the global market. In addition, the rising efforts taken by the major manufacturers to expand therapeutic applications of antipsychotic drugs are also projected to create huge opportunities for the antipsychotics portfolio expansion in near future, thereby boosting the product demands. Johnson & Johnson; Eli Lilly & Co.; Bristol-Myers Squibb; and Pfizer, Inc. are some of the major companies operating in the worldwide antipsychotic drugs market.

In-Depth research report on antipsychotic drugs market:

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