Molecular Weight Markers
Molecular weight (MW) markers are markers used in determining the size of the molecule during electrophoresis. The size allows scientists to estimate the size of other DNA fragments within the molecule. They are also known as DNA, RNA, and protein ladders.
RNA, DNA, and protein markers are MW markers commercially available for testing purposes. Technological innovations such as polymerase chain reaction (PCR) and next-generation sequencing (NGS) allow these markers to be cloned for further research in molecular biology. They are used in detecting viral strains in plants, animals, and humans.
Latest Developments
Thermo Fisher Scientific, one of the leaders in the molecular biology industry, offers a wide variety of ladders for research purposes. Ladders can be used to test base pair lengths ranging from 10 bp (base pairs) to 12 kb (kilo base pairs). These can be stained with ethidium bromide and other DNA stains.
Developments of these markers have culminated in the formation of portable kits to detect and identify diseases. Molecular Detection Inc. (MDI), a US company, launched Detect-Ready tests to detect sepsis and gastrointestinal infections. Recently, it was used to identify Crimean-Congo hemorrhagic fever (CCHF) in Bulgaria. The test allowed the doctors to provide the necessary vaccines and reduce the death rate caused by CCHF.
Market Overview
The worldwide Molecular weight markers market size is expected to exceed USD 1 billion by 2025, according to Grand View Research, Inc. It was valued at USD 355.2 million in 2016. The market demand is driven by the use of these markers in proteomic and biologic applications. It is encouraged by the increasing focus on molecular biology by major corporations.
Major products in the market are protein, DNA, and RNA markers. DNA markers are anticipated a high CAGR over the forecast period (2014 - 2025) due to increased R&D activity in genomics. Pharmaceutical & biotechnology companies are predicted to be the biggest market end-user by the end of the forecast period. Asia Pacific is estimated to exhibit high CAGR during the forthcoming years due to interest of contract research organizations in developing novel drugs. Key players include Thermo Fisher Scientific, Inc.; Qiagen; New England Biolabs; and Promega Corporation.
In-Depth research report on Molecular weight markers market:
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