Tuesday 21 November 2017

Glycomics Research Using Label-free Screening

Glycobiology studies the role and function of carbohydrates in . It studies the function and structure of glycans. These saccharides attract a range of biological molecules through a process known as glycosylation. Glycomics is the pathologic, physiologic, and genetic study of glycomes. This branch of science plays crucial role in development of new drugs, proteomics research, and bacterial physiological analysis.

Label-free Screening Assays for Drug Discovery

In 2017, a Masachusetts-based company, Bruker Corporation announced the launch of MALDI PharmaPulse 2.0 (MPP 2.0) solution. Its advanced laser scanning technology can enhance automation capacity of mass spectrometers. It can help in finding label-free, uHTS (ultra High Throughput Screening) assay that are crucial in drug discovery.

This machine can integrate the required speed of scanning through intricate libraries of different substances with the directness of mass spectrometry. Thereby, allowing mass spectrometry to provide original substrates in the first screening itself. This can prevent false positive or negative results.

The system is made for an automatic treatment of 1536 sample plates to monitor over a million compounds a week. It can save the cost of antibody development. This machine utilizes the company’s patented “Smartbeam 3D laser technology” for speed and direct-detection capability of the mass spectrometry. It can measure nearly 10 samples per second.

Market Summary

According to a report by Grand View Research, Inc., the worldwide glycomics/glycobiology market is expected to surpass USD 2 billion by 2025. Technological advancements can boost the market at a steady CAGR during the forecast period (2014 to 2025). Rising investment in R&D by governments and pharmaceutical & biotechnological research institutes can propel market growth over the coming years.

Market Participants

Key competitors operating in the market for glycobiology are New England Biolabs; ProZyme; Shimadzu Corporation; and Takara Bio, Inc. Major manufacturers provide a range of glycomics products through their distribution channels, around the globe. This is anticipated to increase the vendor competition, putting emphasis on pricing strategies.

In-Depth research report on Glycomics/Glycobiology Market:
http://www.grandviewresearch.com/industry-analysis/glycobiology-market

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