Sunday 19 November 2017

Increased Transplantations to Stem from Development of Nanoparticle-based Drug Delivery Systems

According to the World Health Organization (WHO), organ transplantation is often the last resort for end-stage organ failure. Factors such as loss of blood, leukemia, drug abuse, serious trauma, lack of exercise, and poisoning are resulting in increased occurrence of organ failure. Thus, demand for transplantation products is anticipated to surge in future.

Transplantation of Organs or Tissues

Transplantation is a surgical process in which an organ or tissue is removed from a donor’s body and moved to a recipient’s body, to replace a missing or damaged organ or tissue. The donor may be dead via circulatory death, may be brain dead, or may be living. Some of the organs that have been successfully transplanted are kidneys, lungs, intestine, heart, liver, thymus, and pancreas. Tissues transplanted thus far include musculoskeletal grafts (bones and tendons), veins, nerves, heart valves, and cornea.

Yale Researchers Use Nanoparticles to Curtail Organ Rejection

Organ transplantation has emerged as one of the most remarkable medical innovations. Rapid technological advancements have enhanced the procedure’s efficiency and safety. However, short-term and long-term organ rejection still remains an issue. To address it, researchers are paying increased attention toward the development of innovative techniques. A case in point is a team of researchers from Yale University. In August 2017, the team developed a drug delivery system using nanoparticles. This could curb organ transplant complications by camouflaging donated tissue from the immune system of the recipient.

Besides this, researchers are also focusing on development of artificial transplants with extra features that can potentially benefit human life. For instance, in the same month, researchers at the University of Chicago developed skin grafts using CRISPR gene editing. This can help people with obesity and diabetes to better maintain their glucose levels.

Market Insights

As per the findings of Grand View Research Inc., the global transplantation market is estimated to USD 51.0 billion by 2025. Technological advancements are expected to play an important role in the growth of the market. Development of innovative and novel transplant products such as surgical instruments and tissue products, along with increasing implementation of computerized support systems, can work in favor of the market. Rising incidence of chronic diseases and increasing number of tissue banks are also likely to stoke market growth.

On the other hand, dearth of donors for transplantation process is creating a large gap between demand and supply of organs and tissues for treatment. This is, thereby, estimated to keep the market from realizing its utmost potential. Moreover, customs and religious beliefs are limiting widespread adoption of transplantations.

Some of the prominent companies operating in the market are AbbVie, Inc.; Medtronic; Zimmer Biomet; Stryker; Novartis AG; and Teva Pharmaceuticals.

In-Depth research report on Transplantation Market:

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